I am trying to wrap my head around what a real cocktail was in the past. When I received my HIV diagnoses in 2012 doctors put me on Atripla, a 3-in-1 pill, that very same day. I have not seen any TV show or movie explain what past cocktails where. In the movie Rent, they say "AZT TIME" but never really explain if that is a three times a day thing or 15 times a day thing. Even in the movie Dallas Buyers Club, they go through a list of the medicine but not dosages or dosing schedule. I believe… read more
No problem @A myHIVteam Member. It does take me back so long, the exactness is a bit vague! I remember the indinavir (placebo) was 3 tabs TDS, I took them at 08.00, 16.00 and 00.00 - this meant that for the 3 hours around this (2hrs before and 1 after) I wasn’t allowed to eat more than 5g of fat. Kind of difficult sorting out meals but I did learn that many fruit sweets were virtually fat-free! lol. The TDS abacavir had to be spaced out around this, and remember setting my alarm each night for during the night, as well as taking AZT and 3TC. Did annoy me a bit to find out after nearly 2 years that the indinavir was a placebo and I needn’t have had the fat restriction!!
Abacavir was then put into Combivir (I took with AZT) then abacavir/AZT/3TC was combined into Trizivir, before I went onto Kivexa/AZT. There was quite a bit of controversy regarding kivexa as people were dying from heart problems (hence the alert card), so then went onto Truvada and nevirapine before changing the Truvada to Descovy as it’s better for the kidneys and bone density (kind of glad as have since been diagnosed with hypertrophic cardiomyopathy and osteoporosis).
Jeez, I thought I’d forgotten my meds journey, surprising what’s there if I think hard enough!
@A myHIVteam Member is correct there were no cocktails just AZT of which I never partook of thankfully because of my long denial after diagnosis. By the time I started getting sick, there were other HIV drugs available. I haven't a clue what they were however at one time I was dosing 16 pills throughout the day. Now I am down to 3 pills once a day. Triumeq, prezista, and ritonavir.
I went straight onto a clinical trial (my choice) when diagnosed in ‘98 - either abacavir or indinavir and a placebo. I remember it was over 30 tablets a day, abacavir had no restrictions but indinavir had the possibility of kidney/liver disorders, had to be taken every 8 hours, and <5g of fat 2 hours before and 1 hour after. Initially for 48 wks, they then extended to 72 and further to 96 wks to gain approval for licensing of abacavir. I was pleased to find out that I was on abacavir at the end (later to become a component of Trizivir and Kivexa), but finally swapped as it had its own complications for the liver and also had a black alert card to be carried due to coronary death. Pleased to say now that of my 20-odd tablets a day, only 3 are ARVs - the power of science.
Mine was Zerit and Epiver after AZT nearly killed me
Hey I take Atrpla 3 pill into 1 ever since I was diagnosed in 2009 I have always been undetectable but I never hear anything about that you know about the pill we take I know I supposed to take once a day that's what my doctor say I really hope this help anything you want to talk about it let me know I hope everything going good for you though if you ever want to talk I'm not always on here I'm always on Facebook look me up if you want to John Mitchell hope to hear from you
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