Overview

Trizivir was a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat HIV-1 infection in combination with other antiretroviral medications. Trizivir was a combination drug composed of abacavir, lamivudine, and zidovudine. 

Abacavir, lamivudine, and zidovudine are all antiviral medications of the nucleoside reverse transcriptase inhibitor (NRTI) class. All three drugs are believed to work by preventing HIV from replicating in cells.

How was it taken?

Prescribing information stated that Trizivir was taken twice daily. Trizivir came in tablet form.

Side effects

The FDA-approved label for Trizivir listed common side effects including headache, fatigue, nausea, malaise, and vomiting.

Rare but serious side effects listed for Trizivir included severe hypersensitivity reactions, hematological toxicity (damage to blood cells), myopathy (damage to muscles), lactic acidosis (a metabolic disorder), hepatomegaly (enlarged liver) with steatosis (fatty degeneration), and severe exacerbation of hepatitis B.

For more details about this treatment, visit:

Trizivir — RxList