I'm very curious if there is a new injectable for people living with HIV?I'm on Cabenuva, which is the monthly shot.
There is a new shot out, not sure if it's in Canada or the United States. But awhile back there was a twice yearly shot coming out, but I don't remember which country.
Cabenuva is a two injection every two months.
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(ALWAYS TALK TO YOUR PROVIDER(S) FIRST)
Yes, besides Cabenuva (cabotegravir/rilpivirine), other injectable HIV medicines available or in development include Lenacapavir (Sunlenca/Yeztugo) for treatment/prevention (dosed every 6 months) and Ibalizumab (Trogarzo), plus ongoing trials for combinations like Sunlenca + bNAbs, showing a shift to less frequent, more convenient long-acting options.
Currently Approved Injectable Medications (Beyond Cabenuva):
Lenacapavir (Sunlenca/Yeztugo): A new class (capsid inhibitor) that can be given as a twice-yearly injection for treatment (with other drugs) or prevention (Yeztugo), offering significant convenience.
Ibalizumab (Trogarzo): An antibody treatment (ibalizumab) used for heavily treatment-resistant HIV, administered less frequently than daily pills.
In Development & Future Possibilities:
Lenacapavir Combinations: Trials are exploring combining Lenacapavir with other long-acting agents for even longer intervals (e.g., every 6 months).
Broadly Neutralizing Antibodies (bNAbs): Combinations with Sunlenca are being tested for potential twice-yearly injections.
Novel Drug Candidates: New drugs like VH-184 and VH-499 are showing promise in trials, potentially leading to future long-acting injectables.
Key Trend: The field is moving towards fewer injections (monthly, every few months, or even twice yearly) with drugs like Lenacapavir, offering a major shift from daily oral regimens.
Are there new injectable options beyond Cabenuva for treating HIV?
Yes, there are newer injectable options available! While you're currently on Cabenuva (the monthly shot), there are a couple of additional injectable treatments approved for people living with HIV:
Sunlenca (lenacapavir) - This is a twice-yearly injection Show Full Answer