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Real members of myHIVteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
April 18
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Can you test negative for HIV after exposure while off PrEP, even though you're now back on it?

Yes, this is possible due to the "window period" - the time between HIV exposure and when a test can detect the virus. If you were exposed to HIV while off PrEP and then tested too soon after that exposure, you could receive a Show Full Answer

Can you test negative for HIV after exposure while off PrEP, even though you're now back on it?

Yes, this is possible due to the "window period" - the time between HIV exposure and when a test can detect the virus. If you were exposed to HIV while off PrEP and then tested too soon after that exposure, you could receive a false negative result even though you're infected.

The window period varies by test type:
* NAT tests: 10 to 33 days after exposure
* Antigen/antibody tests (blood draw): 18 to 45 days after exposure
* Rapid antigen/antibody tests (finger stick): 18 to 90 days after exposure
* Antibody tests (most rapid and self-tests): 23 to 90 days after exposure

If you tested during the window period, you should retest after the window period has passed for the specific test type you used. If you had a potential exposure while off PrEP, talk with your doctor about whether you need post-exposure prophylaxis (PEP), which should be started within 72 hours of exposure.

Being back on PrEP now doesn't change whether an earlier exposure resulted in infection - only proper testing after the window period can confirm your status.

April 18

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