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A myHIVteam Member asked a question 💭

After a year and half and my viral load in tact, I’m still exhausted most days.
I’m on Biktarvy, is this still normal?

October 25, 2025
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myHIVteam

Is it normal to still experience fatigue and exhaustion after a year and a half on Biktarvy with an undetectable viral load?

Yes, experiencing fatigue even with an undetectable viral load is something that can happen. While maintaining an undetectable viral load through antiretroviral therapy is the best way to manage HIV Show Full Answer

Is it normal to still experience fatigue and exhaustion after a year and a half on Biktarvy with an undetectable viral load?

Yes, experiencing fatigue even with an undetectable viral load is something that can happen. While maintaining an undetectable viral load through antiretroviral therapy is the best way to manage HIV, fatigue can still occur for several reasons.

Here are some potential causes of ongoing fatigue:

- HIV itself: The virus can cause inflammation in your body and brain, which may drain your energy even when the viral load is controlled
- Mental health conditions: Depression, anxiety, and stress are more common in people living with HIV and can contribute significantly to fatigue
- Comorbid health conditions: Conditions like heart disease, diabetes, or chronic kidney disease can cause exhaustion
- Sleep quality: Poor sleep or disrupted sleep patterns can worsen fatigue
- Diet and nutrition: What you eat can impact your energy levels
- Medication side effects: Some HIV medications can affect sleep or cause fatigue

It's worth discussing this with your healthcare provider. They can help identify what might be contributing to your fatigue and work with you to find solutions, whether that's addressing sleep issues, managing mental health concerns, or exploring other factors.

October 25, 2025
A myHIVteam Member

Yes. I tried Biktarty on two occasions, and it made me feel very exhausted.. So I went back to my previous 4 times daily medication instead.

October 26, 2025

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