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Real members of myHIVteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
August 16, 2025
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For PrEP pills to reach maximum protection
• For anal sex (receptive): Wait 7 consecutive days of taking PrEP
• For vaginal sex: Wait 20-21 consecutive days of taking PrEP

If using injectable PrEP (Apretude), protection typically begins
• About 50% of people are protected after 1 day
• Almost everyone is protected within Show Full Answer

For PrEP pills to reach maximum protection:
• For anal sex (receptive): Wait 7 consecutive days of taking PrEP
• For vaginal sex: Wait 20-21 consecutive days of taking PrEP

If using injectable PrEP (Apretude), protection typically begins:
• About 50% of people are protected after 1 day
• Almost everyone is protected within 7 days after the first injection Important reminders:
• Always take PrEP medications exactly as prescribed
• Regular HIV testing is required every 3 months for pill form, or every 2 months for injectable form
• Discuss any concerns about timing or protection with your healthcare provider, as individual circumstances may vary

August 16, 2025

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San Juan, PR