For PrEP pills to reach maximum protection
• For anal sex (receptive): Wait 7 consecutive days of taking PrEP
• For vaginal sex: Wait 20-21 consecutive days of taking PrEP
If using injectable PrEP (Apretude), protection typically begins
• About 50% of people are protected after 1 day
• Almost everyone is protected within Show Full Answer
For PrEP pills to reach maximum protection:
• For anal sex (receptive): Wait 7 consecutive days of taking PrEP
• For vaginal sex: Wait 20-21 consecutive days of taking PrEP
If using injectable PrEP (Apretude), protection typically begins:
• About 50% of people are protected after 1 day
• Almost everyone is protected within 7 days after the first injection Important reminders:
• Always take PrEP medications exactly as prescribed
• Regular HIV testing is required every 3 months for pill form, or every 2 months for injectable form
• Discuss any concerns about timing or protection with your healthcare provider, as individual circumstances may vary
August 16, 2025