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Real members of myHIVteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myHIVteam Member asked a question 💭
Cincinnati, OH
March 25, 2025
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myHIVteam

Yes, HIV medications, particularly antiretroviral therapy (ART), can cause weight gain. Studies show that people with HIV taking ART medications may gain weight up to three times faster than HIV-negative people of the same age. About 74% of people report gaining weight after starting HIV medication.

This weight gain can be Show Full Answer

Yes, HIV medications, particularly antiretroviral therapy (ART), can cause weight gain. Studies show that people with HIV taking ART medications may gain weight up to three times faster than HIV-negative people of the same age. About 74% of people report gaining weight after starting HIV medication.

This weight gain can be different for each person and may be related to several factors. Some medications, especially those in a class called integrase strand transfer inhibitors, are more associated with weight gain than others. The exact reason why HIV medications cause weight gain isn't fully understood, but research suggests it may be connected to immune system changes. People who start ART with lower CD4 counts or more active immune systems tend to gain more weight, even when the treatment successfully manages their HIV.

If weight gain is significantly impacting your quality of life, talk to your doctor. They may be able to adjust your treatment plan, as some people respond differently to different medications. However, it's crucial never to change your HIV medication regimen without consulting your healthcare provider first.

March 25, 2025
A myHIVteam Member

Don’t forget, it’s very hard to lose the weight once you get it. I know, sitting here with my potbelly.

March 26, 2025

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