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Real members of myHIVteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I've been on Biktarvy since January

October 2
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Answer Summary

Members offered reassurance to someone worried about missing two doses of Biktarvy over a weekend, with the general consensus being that a... Read more

Members offered reassurance to someone worried about missing two doses of Biktarvy over a weekend, with the general consensus being that a short lapse is unlikely to cause harm for someone who has been on medication consistently. Several members noted that while skipping doses regularly can risk viral resistance, missing just a few days occasionally is not the same as developing a pattern, and one member shared a real clinical study showing that a 4-on/3-off dosing schedule maintained viral suppression in many patients. A practical tip that stood out was keeping a day or two of extra pills in your car to avoid missed doses during unplanned trips.

A myHIVteam Member

Thanks so much for that information. I was freaking out but I feel better now. I'm going home tomorrow and I'll be able to take my meds.

October 3
A myHIVteam Member

Thanks so much! I'm back on track now.

October 5
A myHIVteam Member

you'll be ok if you been on meds long. there was a study done (and I participated in that study on my own without the doctor knowing) that you can take your meds 4 days on and 3 days off and nothing changes.
Taking HIV antiretroviral therapy (ART) for 4 consecutive days on followed by 3 days off per week can maintain viral suppression as effectively as continuous daily dosing in specific patients, according to clinical trials like the ANRS 170 QUATUOR study.
Study Overview and Key Findings
• The Trial: The ANRS 170 QUATUOR trial tested 647 participants who already had fully suppressed (undetectable) HIV for at least 12 months.
• Efficacy: At 48 weeks, therapeutic success (maintaining an undetectable viral load) was achieved in 95.6% of the 4-day-on/3-day-off group compared to 97.2% in the continuous 7-day group, meeting non-inferiority standards.
• Benefits: Participants in the intermittent arm reported higher daily life satisfaction and experienced a 43% reduction in treatment costs.
• Caveats: A small number of patients experienced virological failure or drug resistance, meaning this approach is not universally recommended for everyone.

For future references, I'd keep a day or 2 worth of pills in your car for these instances that you forget your meds. Just remember to change them out monthly so they won't expire.

Here is the link to the study:
https://www.sciencedirect.com/science/article/a...

https://www.sciencedirect.com/science/article/abs/pii/S2352301821003003
October 3
A myHIVteam Member

🙈🙈🙈 I prefer not to skip any doses. My infectious disease specialist said that skipping doses can lead to viral resistance.

And I've seen relapses in some people when I go for my checkups, and I don't know if it's because they skipped some doses.

🙈🙈🙈 yo prefiero no saltar ninguna dosis, según mi infectologa dijo que saltarse hay resistencia al virus.
Y he visto recaídas en algunos cuando voy a mis controles, y no sé si es porque se saltearon algunas dosis.

October 2
A myHIVteam Member

You will be fine, only a few days is okay to miss. When I was first diagnosed I was so afraid if I missed a pill I'd get sick, like right away. That doesn't happen and as long as its not often your virus will not become resistant.

October 5

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