I believe it was older Truvada they have changed the meds that go into it and now it's used for PrEP more than an ART these days.
June 26
Yeah..Ive taken both and ended up with 2 damaged vertebrae..now its 3..with a popping noise..Any side effects reported by women with Cabenuva and will this medication worsen my bone loss..the doctor passed both off as old age
June 23
That's a really valid concern, and it can be frustrating when information seems hard to find. Bone loss is a known issue for people living with HIV, and certain antiretroviral medications have been linked to it.
The main culprits that have been associated with bone loss include:
- Tenofovir disoproxil fumarate (TDF) — Show Full Answer
That's a really valid concern, and it can be frustrating when information seems hard to find. Bone loss is a known issue for people living with HIV, and certain antiretroviral medications have been linked to it.
The main culprits that have been associated with bone loss include:
- Tenofovir disoproxil fumarate (TDF) — sold under brand names like Viread, and found in combination pills like Truvada and Atripla. This is the one most commonly linked to lawsuits related to bone and kidney damage.
- Some older protease inhibitors — used in earlier HIV treatment regimens.
TDF in particular was at the center of legal action, with claims that the manufacturer knew of risks and delayed introducing a safer alternative (tenofovir alafenamide, or TAF), which has a better bone and kidney safety profile. If you're concerned about bone health, it's worth asking your doctor about:
- A bone density scan (DEXA scan)
- Whether your current regimen includes TDF
- Vitamin D and calcium levels, as deficiencies are common with HIV and can worsen bone loss
Switching to a TAF-based regimen may be an option worth discussing if bone health is a concern for you.
June 23
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