Answer Summary

Members widely confirmed experiencing significant weight gain on Biktarvy, with many reporting increases ranging from 14 to 80 pounds, often... Read more

Members widely confirmed experiencing significant weight gain on Biktarvy, with many reporting increases ranging from 14 to 80 pounds, often within just a few months of starting treatment, with several acknowledging the challenge of losing the weight despite exercise and dietary changes. Several members shared that switching to Dovato helped them stop gaining or even lose weight, as it contains only two medications and lacks TAF, a component in both Biktarvy and Genvoya known to be associated with weight gain. A recurring theme was the difficult emotional balance between gratitude for effective HIV treatment and frustration with unwanted physical changes, with members encouraging each other to advocate with their doctors about alternative medications.