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Real members of myHIVteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myHIVteam Member asked a question 💭
Barrie, ON

Can Dovato cause severe muscle and bone pain? As I was getting up from the couch, my right leg got severely weak and I almost fell to the floor and hit my head. Ever since I started to be taking Dovato again, my muscles and bones have been weak and in pain. I see my doctor on the 11th of this month and I will be telling him/her about, what I am experiencing with my health.

September 2
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myHIVteam

Can Dovato cause severe muscle and bone pain? Yes, muscle and bone-related side effects are worth taking seriously, especially given what's being experienced.

Dovato contains two medications: dolutegravir and lamivudine. While it's generally well-tolerated, some people do report muscle weakness, bone pain, and joint Show Full Answer

Can Dovato cause severe muscle and bone pain? Yes, muscle and bone-related side effects are worth taking seriously, especially given what's being experienced.

Dovato contains two medications: dolutegravir and lamivudine. While it's generally well-tolerated, some people do report muscle weakness, bone pain, and joint discomfort while taking it.

A few things worth knowing before the doctor's appointment: - Bone density loss can be a concern with some HIV medications, and Dovato's components have been associated with this in some people
- Muscle weakness severe enough to cause near-falls is something that should be flagged as urgent — don't wait if it gets worse before the 11th
- Vitamin D and calcium levels are sometimes checked in people on HIV treatment, as deficiencies can worsen bone and muscle symptoms

It's really good that the doctor's appointment is already scheduled. When going in, be specific about the timeline — mentioning that symptoms started or worsened after restarting Dovato is really important context for the doctor.

If the leg weakness happens again suddenly or gets worse, that's worth an urgent or emergency visit rather than waiting. Safety first! 🙏

September 2
A myHIVteam Member

I’ve been taking Dovato for years. I don’t have a problem with it. My body aches from getting older and doing things like still cutting the grass doing grocery shopping carrying groceries. My body kills me every day, but I’m not one not to sit still neither so my muscles hurt yes but I’m not sure if it’s from the Dovato I mean my body is in pain all the time you know thank God I’ve been living good with. HIV I don’t have any issues. None with my HIV at all thank God I don’t have anything I get diarrhea. I get nauseous but I other medicines also and I have other sicknesses so you have to look at the whole big picture, it’s not just HIV. You have other sicknesses in your body that you’re dealing with different kind of pills different kind of medication‘s got a lot to do with everything. I drink plenty electrolyte water. I get it from the dollar tree 1:50 a big bottle of electrolyte water and it keeps me healthy The bottle does not make me gain weight still the same size just going through a lot of different things but it’s OK. I’m good. I’m real good. Have a blessed day. Blessed night. Later. 🥰

September 2 (edited)
A myHIVteam Member

Dovato causes weight gain, alters good cholesterol, and produces osteoarthritis, although the manufacturer already indicates this in its package insert.
In Europe, more than 67% of those taking Dovato suffer from chronic osteoarthritis; obviously, it doesn't destroy your kidneys like other antivirals.
It's important to be aware that all the antivirals in the three different triads that are prescribed never passed phase 2 and 3 trials; their effects are directly evaluated in the end patient.
SAD but TRUE.

El Dovato aumenta de peso, altera el colesterol bueno y produce ARTROSIS, aunque ya lo indica el laboratorio en su prospecto.
En Europa, mas del 67% que toma Dovato sufre de ARTROSIS CRONICA, evidentemente no te destroza los Riñones como el resto de retros.
Hay que ser consciente de que todos los Antivirales en las tres triadas diferentes que se recetan, nunca pasaron los ensayos de fase 2 y 3 ,directamente se evalúan sus efectos con el paciente final.
TRISTE pero REAL.

September 2

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