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Real members of myHIVteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myHIVteam Subscriber asked a question 💭
July 17
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Great question — and yes, the liver and kidneys are worth keeping an eye on with some HIV medications (and it sounds like autocorrect had a little fun with "lover" there 😄).

Some antiretrovirals (ARVs), particularly older forms of tenofovir (TDF), have been linked to kidney and bone density issues with long-term use. A Show Full Answer

Great question — and yes, the liver and kidneys are worth keeping an eye on with some HIV medications (and it sounds like autocorrect had a little fun with "lover" there 😄).

Some antiretrovirals (ARVs), particularly older forms of tenofovir (TDF), have been linked to kidney and bone density issues with long-term use. A newer version, TAF, was developed specifically to reduce those risks. Signs of liver problems to watch for while on HIV treatment include:

- Dark urine
- Yellowing of skin or eyes (jaundice)
- Nausea or vomiting
- Loss of appetite for several days
- Itching
- Light-colored stools
- Pain or tenderness on the right side of your abdomen

If any of these show up, it's important to contact a healthcare provider right away. Injectable treatments like Cabenuva can also carry a risk of liver toxicity, especially for those with a prior hepatitis B or C diagnosis.

The good news is that healthcare providers routinely monitor kidney and liver function through blood and urine tests, so these risks are closely managed. Always let your doctor know about any new symptoms.

July 17

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